NIPT analyses cell-free DNA circulating in the pregnant mother’s blood. It is a new option in prenatal screening for Down syndrome (trisomy 21) and other common fetal chromosomal conditions (trisomies 18 and 13). As no invasive procedure is required in obtaining the sample, there is no risk of miscarriage.
The test identifies more than 99% of fetuses with trisomy 21, more than 96% of fetuses with trisomy 18, and more than 93% of fetuses with trisomy 13. This test can also evaluate sex chromosome conditions. A trisomy is a chromosome condition that occurs when there are 3 copies of a particular chromosome instead of 2. Trisomy 21 causes Down syndrome, trisomy 18 causes Edwards syndrome and trisomy 13 causes Patau syndrome.
Twins – Twins pregnancies including IVF are eligible for Harmony (Trisomy 21,18,13) with or without Fetal Sex Option.
IVF – No restriction on pregnancies involving egg donor.
In additional to chromosomal abnormalities, you may screen for five microdeletion syndromes ( 22q11.2, 1p36, Cri-du-chat, Angelman, & Prader-Willi syndrome).
Panorama is the only NIPT that is validated to screen for triploidy.